Clsi Document M45 Pdf

The primary goal of CLSI M45 is to provide essential guidance for antimicrobial susceptibility testing (AST) when resistance is a concern and the organism's susceptibility cannot be predicted by its identity alone.

Most commercial automated AST systems are optimized for rapidly growing, non-fastidious bacteria. When a lab encounters an organism like Corynebacterium jeikeium , automated cards may not be validated. The CLSI M45 PDF serves as the definitive manual reference to set up manual broth microdilution or agar dilution. 2. Clinical Relevance and Breakpoints clsi document m45 pdf