The existence of these patched versions is a direct response to the constant war between cheat developers and anti-cheat systems. The methods used are a fascinating evolution of defense and counter-defense:

If you want to use Cheat Engine for single-player games, follow these safety guidelines to protect your digital security: Download Only From Official Sources

Cheat Engine is legally designed as an educational tool for learning programming, debugging, and memory manipulation. Attempting to "patch" it to gain an unfair advantage in competitive online games violates the Terms of Service (TOS) and End-User License Agreements (EULA) of those titles. Stick to using the software on single-player titles or games explicitly designed for modding. 3. Rely on Trusted Communities